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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PKN2
All Species:
21.21
Human Site:
T133
Identified Species:
35.9
UniProt:
Q16513
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16513
NP_006247.1
984
112035
T133
N
N
D
P
R
C
S
T
S
N
N
R
L
K
A
Chimpanzee
Pan troglodytes
XP_001145367
984
112028
T133
N
N
D
P
R
C
S
T
S
N
N
R
L
K
A
Rhesus Macaque
Macaca mulatta
XP_001110500
1011
111864
A212
A
S
G
P
R
P
W
A
E
Q
L
R
A
R
H
Dog
Lupus familis
XP_547295
1021
115999
T171
N
S
D
P
R
C
S
T
S
S
N
R
L
M
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8BWW9
983
111611
T133
N
S
D
S
R
S
S
T
S
N
N
R
L
M
A
Rat
Rattus norvegicus
O08874
985
112050
T133
N
S
D
S
R
S
S
T
S
N
N
R
R
L
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506565
993
109767
E200
P
D
P
C
R
W
E
E
K
P
V
A
R
R
V
Chicken
Gallus gallus
XP_422357
1013
114806
T161
N
S
D
P
R
F
P
T
N
N
R
L
M
A
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_700704
970
110327
T121
K
S
E
S
R
T
C
T
S
S
S
R
L
A
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13678
634
71138
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34885
707
80133
Sea Urchin
Strong. purpuratus
XP_787090
799
90414
G31
Q
S
R
Q
I
P
T
G
E
K
E
A
G
E
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P24583
1151
131500
Q199
N
D
I
M
D
N
Q
Q
P
K
F
R
R
K
Q
Red Bread Mold
Neurospora crassa
P87253
1142
127954
L161
H
L
G
P
R
I
Q
L
M
L
S
Q
I
Q
F
Conservation
Percent
Protein Identity:
100
99.6
46.1
92.8
N.A.
94.6
92.6
N.A.
53.9
87
N.A.
76.4
N.A.
28.3
N.A.
27.6
48.4
Protein Similarity:
100
99.9
63.2
94.7
N.A.
97.2
95.3
N.A.
68.2
91.9
N.A.
85
N.A.
42.3
N.A.
43.7
61.3
P-Site Identity:
100
100
20
80
N.A.
73.3
60
N.A.
6.6
40
N.A.
40
N.A.
0
N.A.
0
0
P-Site Similarity:
100
100
33.3
93.3
N.A.
80
66.6
N.A.
20
60
N.A.
66.6
N.A.
0
N.A.
0
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
26.1
27.2
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
45.6
45.9
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
46.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
0
8
0
0
0
15
8
15
36
% A
% Cys:
0
0
0
8
0
22
8
0
0
0
0
0
0
0
0
% C
% Asp:
0
15
43
0
8
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
8
0
0
0
8
8
15
0
8
0
0
8
0
% E
% Phe:
0
0
0
0
0
8
0
0
0
0
8
0
0
0
8
% F
% Gly:
0
0
15
0
0
0
0
8
0
0
0
0
8
0
0
% G
% His:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
0
0
8
0
8
8
0
0
0
0
0
0
8
0
0
% I
% Lys:
8
0
0
0
0
0
0
0
8
15
0
0
0
22
0
% K
% Leu:
0
8
0
0
0
0
0
8
0
8
8
8
36
8
8
% L
% Met:
0
0
0
8
0
0
0
0
8
0
0
0
8
15
8
% M
% Asn:
50
15
0
0
0
8
0
0
8
36
36
0
0
0
0
% N
% Pro:
8
0
8
43
0
15
8
0
8
8
0
0
0
0
0
% P
% Gln:
8
0
0
8
0
0
15
8
0
8
0
8
0
8
8
% Q
% Arg:
0
0
8
0
72
0
0
0
0
0
8
58
22
15
0
% R
% Ser:
0
50
0
22
0
15
36
0
43
15
15
0
0
0
0
% S
% Thr:
0
0
0
0
0
8
8
50
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
15
% V
% Trp:
0
0
0
0
0
8
8
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _